{"id":73,"date":"2025-09-11T21:43:59","date_gmt":"2025-09-11T21:43:59","guid":{"rendered":"https:\/\/sites.tntech.edu\/lhnguyen\/?page_id=73"},"modified":"2026-10-05T01:23:17","modified_gmt":"2026-10-05T01:23:17","slug":"feature-research","status":"publish","type":"page","link":"https:\/\/sites.tntech.edu\/lhnguyen\/","title":{"rendered":"Featured Research"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\" style=\"font-size:16px\"><strong>Scientific Perspective<\/strong><\/p>\n\n\n\n<figure data-wp-context=\"{&quot;imageId&quot;:&quot;6ae28c0e58e26&quot;}\" data-wp-interactive=\"core\/image\" data-wp-key=\"6ae28c0e58e26\" class=\"wp-block-image size-full is-resized wp-lightbox-container\"><img loading=\"lazy\" decoding=\"async\" width=\"650\" height=\"532\" data-wp-class--hide=\"state.isContentHidden\" data-wp-class--show=\"state.isContentVisible\" data-wp-init=\"callbacks.setButtonStyles\" data-wp-on--click=\"actions.showLightbox\" data-wp-on--load=\"callbacks.setButtonStyles\" data-wp-on--pointerdown=\"actions.preloadImage\" data-wp-on--pointerenter=\"actions.preloadImageWithDelay\" data-wp-on--pointerleave=\"actions.cancelPreload\" data-wp-on-window--resize=\"callbacks.setButtonStyles\" src=\"https:\/\/sites.tntech.edu\/lhnguyen\/wp-content\/uploads\/sites\/177\/2026\/08\/TOC-Graphic_V2.png\" alt=\"\" class=\"wp-image-227\" style=\"width:292px;height:auto\" srcset=\"https:\/\/sites.tntech.edu\/lhnguyen\/wp-content\/uploads\/sites\/177\/2026\/08\/TOC-Graphic_V2.png 650w, https:\/\/sites.tntech.edu\/lhnguyen\/wp-content\/uploads\/sites\/177\/2026\/08\/TOC-Graphic_V2-300x246.png 300w\" sizes=\"auto, (max-width: 650px) 100vw, 650px\" \/><button\n\t\t\tclass=\"lightbox-trigger\"\n\t\t\ttype=\"button\"\n\t\t\taria-haspopup=\"dialog\"\n\t\t\tdata-wp-bind--aria-label=\"state.thisImage.triggerButtonAriaLabel\"\n\t\t\tdata-wp-init=\"callbacks.initTriggerButton\"\n\t\t\tdata-wp-on--click=\"actions.showLightbox\"\n\t\t\tdata-wp-style--right=\"state.thisImage.buttonRight\"\n\t\t\tdata-wp-style--top=\"state.thisImage.buttonTop\"\n\t\t>\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"12\" height=\"12\" fill=\"none\" viewBox=\"0 0 12 12\">\n\t\t\t\t<path fill=\"#fff\" d=\"M2 0a2 2 0 0 0-2 2v2h1.5V2a.5.5 0 0 1 .5-.5h2V0H2Zm2 10.5H2a.5.5 0 0 1-.5-.5V8H0v2a2 2 0 0 0 2 2h2v-1.5ZM8 12v-1.5h2a.5.5 0 0 0 .5-.5V8H12v2a2 2 0 0 1-2 2H8Zm2-12a2 2 0 0 1 2 2v2h-1.5V2a.5.5 0 0 0-.5-.5H8V0h2Z\" \/>\n\t\t\t<\/svg>\n\t\t<\/button><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:16px\">Our perspective identifies common limitations in current practices in COF structure determination and illustrates the importance of collecting sufficient evidence to avoid mismatches between experimental data and proposed COF models. (<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.2132280?utm_source=researchgate.net&amp;utm_medium=article\"><em>Angew. Chem. Int. Ed.<\/em> <strong>2026<\/strong>, <em>65<\/em>, e2132280<\/a>).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:16px\"><strong>Covalent organic framework-309 (COF-309)<\/strong><\/p>\n\n\n\n<figure data-wp-context=\"{&quot;imageId&quot;:&quot;6ae28c0e59544&quot;}\" data-wp-interactive=\"core\/image\" data-wp-key=\"6ae28c0e59544\" class=\"wp-block-image size-large is-resized wp-lightbox-container\"><img loading=\"lazy\" decoding=\"async\" width=\"770\" height=\"1024\" data-wp-class--hide=\"state.isContentHidden\" data-wp-class--show=\"state.isContentVisible\" data-wp-init=\"callbacks.setButtonStyles\" data-wp-on--click=\"actions.showLightbox\" data-wp-on--load=\"callbacks.setButtonStyles\" data-wp-on--pointerdown=\"actions.preloadImage\" data-wp-on--pointerenter=\"actions.preloadImageWithDelay\" data-wp-on--pointerleave=\"actions.cancelPreload\" data-wp-on-window--resize=\"callbacks.setButtonStyles\" src=\"https:\/\/sites.tntech.edu\/lhnguyen\/wp-content\/uploads\/sites\/177\/2025\/09\/image-4-770x1024.png\" alt=\"\" class=\"wp-image-75\" style=\"width:292px;height:auto\" srcset=\"https:\/\/sites.tntech.edu\/lhnguyen\/wp-content\/uploads\/sites\/177\/2025\/09\/image-4-770x1024.png 770w, https:\/\/sites.tntech.edu\/lhnguyen\/wp-content\/uploads\/sites\/177\/2025\/09\/image-4-226x300.png 226w, https:\/\/sites.tntech.edu\/lhnguyen\/wp-content\/uploads\/sites\/177\/2025\/09\/image-4-768x1021.png 768w, https:\/\/sites.tntech.edu\/lhnguyen\/wp-content\/uploads\/sites\/177\/2025\/09\/image-4-1155x1536.png 1155w, https:\/\/sites.tntech.edu\/lhnguyen\/wp-content\/uploads\/sites\/177\/2025\/09\/image-4-1540x2048.png 1540w, https:\/\/sites.tntech.edu\/lhnguyen\/wp-content\/uploads\/sites\/177\/2025\/09\/image-4-scaled.png 1925w\" sizes=\"auto, (max-width: 770px) 100vw, 770px\" \/><button\n\t\t\tclass=\"lightbox-trigger\"\n\t\t\ttype=\"button\"\n\t\t\taria-haspopup=\"dialog\"\n\t\t\tdata-wp-bind--aria-label=\"state.thisImage.triggerButtonAriaLabel\"\n\t\t\tdata-wp-init=\"callbacks.initTriggerButton\"\n\t\t\tdata-wp-on--click=\"actions.showLightbox\"\n\t\t\tdata-wp-style--right=\"state.thisImage.buttonRight\"\n\t\t\tdata-wp-style--top=\"state.thisImage.buttonTop\"\n\t\t>\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"12\" height=\"12\" fill=\"none\" viewBox=\"0 0 12 12\">\n\t\t\t\t<path fill=\"#fff\" d=\"M2 0a2 2 0 0 0-2 2v2h1.5V2a.5.5 0 0 1 .5-.5h2V0H2Zm2 10.5H2a.5.5 0 0 1-.5-.5V8H0v2a2 2 0 0 0 2 2h2v-1.5ZM8 12v-1.5h2a.5.5 0 0 0 .5-.5V8H12v2a2 2 0 0 1-2 2H8Zm2-12a2 2 0 0 1 2 2v2h-1.5V2a.5.5 0 0 0-.5-.5H8V0h2Z\" \/>\n\t\t\t<\/svg>\n\t\t<\/button><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:16px\">COF-309 with high hydrophilicity index breaks the record of water working capacity in water-harvesting COFs. Our hydrophilicity index equation can be used to \u2018pinpoint\u2019 the onset position of water harvesting isotherms using reticular materials (<a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acscentsci.4c01878\" data-type=\"link\" data-id=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acscentsci.4c01878\"><em>ACS Cent. Sci.<\/em>&nbsp;<strong>2025<\/strong>,&nbsp;<em>11<\/em>, 665\u2013671<\/a>).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:16px\"><strong>Covalent organic framework-39 (COF-39)<\/strong><\/p>\n\n\n\n<figure data-wp-context=\"{&quot;imageId&quot;:&quot;6ae28c0e59bfe&quot;}\" data-wp-interactive=\"core\/image\" data-wp-key=\"6ae28c0e59bfe\" class=\"wp-block-image size-large is-resized wp-lightbox-container\"><img loading=\"lazy\" decoding=\"async\" width=\"684\" height=\"1024\" data-wp-class--hide=\"state.isContentHidden\" data-wp-class--show=\"state.isContentVisible\" data-wp-init=\"callbacks.setButtonStyles\" data-wp-on--click=\"actions.showLightbox\" data-wp-on--load=\"callbacks.setButtonStyles\" data-wp-on--pointerdown=\"actions.preloadImage\" data-wp-on--pointerenter=\"actions.preloadImageWithDelay\" data-wp-on--pointerleave=\"actions.cancelPreload\" data-wp-on-window--resize=\"callbacks.setButtonStyles\" src=\"https:\/\/sites.tntech.edu\/lhnguyen\/wp-content\/uploads\/sites\/177\/2025\/09\/image-5-684x1024.png\" alt=\"\" class=\"wp-image-76\" style=\"width:291px;height:auto\" srcset=\"https:\/\/sites.tntech.edu\/lhnguyen\/wp-content\/uploads\/sites\/177\/2025\/09\/image-5-684x1024.png 684w, https:\/\/sites.tntech.edu\/lhnguyen\/wp-content\/uploads\/sites\/177\/2025\/09\/image-5-201x300.png 201w, https:\/\/sites.tntech.edu\/lhnguyen\/wp-content\/uploads\/sites\/177\/2025\/09\/image-5-768x1149.png 768w, https:\/\/sites.tntech.edu\/lhnguyen\/wp-content\/uploads\/sites\/177\/2025\/09\/image-5.png 792w\" sizes=\"auto, (max-width: 684px) 100vw, 684px\" \/><button\n\t\t\tclass=\"lightbox-trigger\"\n\t\t\ttype=\"button\"\n\t\t\taria-haspopup=\"dialog\"\n\t\t\tdata-wp-bind--aria-label=\"state.thisImage.triggerButtonAriaLabel\"\n\t\t\tdata-wp-init=\"callbacks.initTriggerButton\"\n\t\t\tdata-wp-on--click=\"actions.showLightbox\"\n\t\t\tdata-wp-style--right=\"state.thisImage.buttonRight\"\n\t\t\tdata-wp-style--top=\"state.thisImage.buttonTop\"\n\t\t>\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"12\" height=\"12\" fill=\"none\" viewBox=\"0 0 12 12\">\n\t\t\t\t<path fill=\"#fff\" d=\"M2 0a2 2 0 0 0-2 2v2h1.5V2a.5.5 0 0 1 .5-.5h2V0H2Zm2 10.5H2a.5.5 0 0 1-.5-.5V8H0v2a2 2 0 0 0 2 2h2v-1.5ZM8 12v-1.5h2a.5.5 0 0 0 .5-.5V8H12v2a2 2 0 0 1-2 2H8Zm2-12a2 2 0 0 1 2 2v2h-1.5V2a.5.5 0 0 0-.5-.5H8V0h2Z\" \/>\n\t\t\t<\/svg>\n\t\t<\/button><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:16px\">COF-39 is the first 3D COF formed by entanglement of 2D squares. This specific design relies on a flexible distorted tetrahedral linker which, when linked to linear amines, allows the interpenetration of the square net \u2013 entangled square structure (<a href=\"https:\/\/pubs.acs.org\/doi\/full\/10.1021\/jacs.1c13468\" data-type=\"link\" data-id=\"https:\/\/pubs.acs.org\/doi\/full\/10.1021\/jacs.1c13468\"><em>J. Am. Chem. Soc.<\/em>&nbsp;<strong>2022<\/strong>,&nbsp;<em>144<\/em>, 1539\u20131544<\/a>).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:16px\"><strong>Covalent organic framework-790 (COF-790)<\/strong><\/p>\n\n\n\n<figure data-wp-context=\"{&quot;imageId&quot;:&quot;6ae28c0e5a2fe&quot;}\" data-wp-interactive=\"core\/image\" data-wp-key=\"6ae28c0e5a2fe\" class=\"wp-block-image size-large is-resized wp-lightbox-container\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"988\" data-wp-class--hide=\"state.isContentHidden\" data-wp-class--show=\"state.isContentVisible\" data-wp-init=\"callbacks.setButtonStyles\" data-wp-on--click=\"actions.showLightbox\" data-wp-on--load=\"callbacks.setButtonStyles\" data-wp-on--pointerdown=\"actions.preloadImage\" data-wp-on--pointerenter=\"actions.preloadImageWithDelay\" data-wp-on--pointerleave=\"actions.cancelPreload\" data-wp-on-window--resize=\"callbacks.setButtonStyles\" src=\"https:\/\/sites.tntech.edu\/lhnguyen\/wp-content\/uploads\/sites\/177\/2025\/09\/image-3-1024x988.png\" alt=\"\" class=\"wp-image-74\" style=\"width:295px;height:auto\" srcset=\"https:\/\/sites.tntech.edu\/lhnguyen\/wp-content\/uploads\/sites\/177\/2025\/09\/image-3-1024x988.png 1024w, https:\/\/sites.tntech.edu\/lhnguyen\/wp-content\/uploads\/sites\/177\/2025\/09\/image-3-300x289.png 300w, https:\/\/sites.tntech.edu\/lhnguyen\/wp-content\/uploads\/sites\/177\/2025\/09\/image-3-768x741.png 768w, https:\/\/sites.tntech.edu\/lhnguyen\/wp-content\/uploads\/sites\/177\/2025\/09\/image-3-1536x1482.png 1536w, https:\/\/sites.tntech.edu\/lhnguyen\/wp-content\/uploads\/sites\/177\/2025\/09\/image-3-2048x1976.png 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><button\n\t\t\tclass=\"lightbox-trigger\"\n\t\t\ttype=\"button\"\n\t\t\taria-haspopup=\"dialog\"\n\t\t\tdata-wp-bind--aria-label=\"state.thisImage.triggerButtonAriaLabel\"\n\t\t\tdata-wp-init=\"callbacks.initTriggerButton\"\n\t\t\tdata-wp-on--click=\"actions.showLightbox\"\n\t\t\tdata-wp-style--right=\"state.thisImage.buttonRight\"\n\t\t\tdata-wp-style--top=\"state.thisImage.buttonTop\"\n\t\t>\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"12\" height=\"12\" fill=\"none\" viewBox=\"0 0 12 12\">\n\t\t\t\t<path fill=\"#fff\" d=\"M2 0a2 2 0 0 0-2 2v2h1.5V2a.5.5 0 0 1 .5-.5h2V0H2Zm2 10.5H2a.5.5 0 0 1-.5-.5V8H0v2a2 2 0 0 0 2 2h2v-1.5ZM8 12v-1.5h2a.5.5 0 0 0 .5-.5V8H12v2a2 2 0 0 1-2 2H8Zm2-12a2 2 0 0 1 2 2v2h-1.5V2a.5.5 0 0 0-.5-.5H8V0h2Z\" \/>\n\t\t\t<\/svg>\n\t\t<\/button><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:16px\">Using conformational design through geometrical constraint, we designed and successfully synthesized COF-790 bearing a single framework of a new COF topology (<strong>fjh<\/strong>). This strategy is applicable for various structures and can be used to diversify the chemistry of 3D COFs (<a href=\"https:\/\/pubs.acs.org\/doi\/full\/10.1021\/jacs.0c11064\" data-type=\"link\" data-id=\"https:\/\/pubs.acs.org\/doi\/full\/10.1021\/jacs.0c11064\"><em>J. Am. Chem. Soc.<\/em>&nbsp;<strong>2020<\/strong>,&nbsp;<em>142<\/em>, 20335\u201320339<\/a>).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scientific Perspective Our perspective identifies common limitations in current practices in COF structure determination and illustrates &hellip;<\/p>\n<p class=\"read-more\"> <a class=\"more-link\" href=\"https:\/\/sites.tntech.edu\/lhnguyen\/\"> <span class=\"screen-reader-text\">Featured Research<\/span> Read more \u2192<\/a><\/p>\n","protected":false},"author":206,"featured_media":85,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-73","page","type-page","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/sites.tntech.edu\/lhnguyen\/wp-json\/wp\/v2\/pages\/73","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.tntech.edu\/lhnguyen\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.tntech.edu\/lhnguyen\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.tntech.edu\/lhnguyen\/wp-json\/wp\/v2\/users\/206"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.tntech.edu\/lhnguyen\/wp-json\/wp\/v2\/comments?post=73"}],"version-history":[{"count":21,"href":"https:\/\/sites.tntech.edu\/lhnguyen\/wp-json\/wp\/v2\/pages\/73\/revisions"}],"predecessor-version":[{"id":264,"href":"https:\/\/sites.tntech.edu\/lhnguyen\/wp-json\/wp\/v2\/pages\/73\/revisions\/264"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sites.tntech.edu\/lhnguyen\/wp-json\/wp\/v2\/media\/85"}],"wp:attachment":[{"href":"https:\/\/sites.tntech.edu\/lhnguyen\/wp-json\/wp\/v2\/media?parent=73"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}